Stimulants. Stimulants Substances stimulants

Sexual decline is a serious problem that can arise in the life of every man, regardless of age. Sexual health is the foundation for men's self-confidence and self-confidence. But a polluted environment, unhealthy diet, smoking and other bad habits, constant stress, various diseases - all this leads to a decrease in the level of potency, therefore, the demand for male potency stimulants increases.

When problems with erection occur, many representatives of the strong half of humanity panic. Do not despair - there are special stimulants that help to quickly and effectively restore and improve erectile function. In such cases, male potency stimulants are used, which can be conditionally divided into several categories - natural, medicinal and home remedies.

What is male potency

Erectile function plays an extremely important role in men's health. Without a full-fledged level of potency, it is impossible to imagine the psychological and physical well-being of a modern man. Not surprisingly, for every man, maintaining a healthy level of erectile function is a top priority.

Potency is the male ability to have intercourse that is independent of male reproductive health. The erectile function of the male body conventionally consists of 3 main stages:

  1. Excitation- this is the name of the physiological reaction of the male body, which arises as a result of the influence of certain factors of a tactile and psychological nature.
  2. Erection- This condition is the result of successful arousal and is characterized by a contraction of muscle fibers in the area of ​​the base of the penis and an accelerated blood flow to the tissues of the penis.
  3. Ejaculation- the final stage of sexual arousal, during which there is a relaxation of tense muscle tissues, blood outflow and ejaculation itself.

Quite often, representatives of the strong half complain of a deterioration in potency, a decrease in erection, or its short duration. The main reasons for the deterioration of erectile function can be associated with factors of an external, internal or age-related nature.

The most common external factors include polluted environmental conditions and drinking water, negative effects of radiation and electromagnetic fields, as well as professional activities associated with hazardous industrial conditions.

Internal causes are most often associated with a sedentary lifestyle and lack of physical activity, as a result of which the normal process of blood flow in the male pelvic organs is disrupted. Internal factors also include diseases and various injuries of the genital organs, as a result of which they lose the ability to normally perform their functional purpose.

The main signs of erectile dysfunction:

  • A man has a weakened sexual desire, sexual arousal is achieved much more difficult than usual.
  • Sexual intercourse lasts a short time, and premature ejaculation may also occur.
  • There are problems with an erection, or its duration.
  • In the process of sexual contact, a man has difficulty reaching orgasm.

Problems with erectile function can occur in men at any age. In case of the first signs of impotence, it is necessary to seek medical help from a sex therapist, who will help establish the cause of the deterioration of erection and choose the optimal stimulator of male potency.

The main types of male potency stimulants

All stimulants used to increase potency are conventionally divided into several groups, among which natural and synthetic stimulants can be distinguished.

Natural sex stimulants- these are herbal preparations, various biologically active additives, as well as food products that increase the level of potency.
Synthetic potency stimulants Are drugs that effectively normalize erectile function.
Each of these methods has many advantages, and therefore can be used to treat erectile dysfunction - both independently and in combination, in combination with other methods of increasing potency. And also various electrostimulators of potency of men and vacuum pumps for the penis can be used.

It is important to remember that before using any stimulants of male potency, it is imperative to consult with a urologist and sex therapist, since the cause of a decrease in erection can be a serious disease of the genitals. Timely medical assistance will cure the disease and restore the health of the male reproductive system.

Natural stimulants of male potency

Natural aphrodisiacs and proper nutrition

One of the most important roles in maintaining a high level of potency is given to proper nutrition. A well-designed diet allows you to restore the normal functioning of the male reproductive system, as well as prevent the further development of impotence.

To improve an erection, you must regularly include the following foods in your menu:

  • Any kind of meat. The most beneficial for men's health are considered to be low-fat meat dishes cooked together with spices, spices and herbs.
  • Seafood in any form - mussels, oysters, shrimps, lobsters, crabs are especially useful.
  • Nuts are the best natural potency stimulants. Any nuts are useful - walnuts, almonds, peanuts, hazelnuts.
  • Avocados, pomegranates, figs, oranges are natural potency stimulants, which in their effectiveness are in no way inferior to pharmacological preparations.
  • Animal fats, which must make up at least 35% of the daily diet.
  • Spices, herbs and spices - horseradish, dill, parsley, onion, garlic, celery, basil, cumin, nutmeg.

Natural potency stimulants

Many representatives of the strong half of humanity are absolutely sure that the best pathogen for men is various means of natural origin. Natural stimulants for men can be roughly divided into two subgroups - combined herbal preparations and biologically active additives (dietary supplements).

Effective potency stimulants- these are various dietary supplements and homeopathic medicines. Such funds include Laveron, Sealex, Ogopleks, Alikaps, Orgazeks, Verona. Such potency stimulants for men contain a huge amount of vitamins, amino acids and useful trace elements, which have the most positive effect on the state of the male reproductive system.

Erectile stimulants differ from conventional medications in a longer regimen. A potency stimulator at home should be taken 1-2 capsules per day, for at least 30 days. In this case, you can notice an intense improvement in erection and an improvement in the condition of the male reproductive sphere. But there are those that are taken on a pill just before intercourse, activating blood flow to the organs of the reproductive system and increasing erection.

Stimulation of potency with natural ingredients Is one of the most effective and fast-acting methods of restoring erectile function. Stimulants are natural and completely safe, they do not pose any harm to men's health.

  • Alcohol tincture of ginseng root- sold in any pharmacy and can be used to improve erection. To do this, 30 drops of tincture must be dissolved in a glass of water and taken twice a day. The duration of treatment is at least 30 days.
  • Dubrovnik- 4–5 tablespoons of pre-crushed raw materials should be poured with 2 cups of boiling water and left for half an hour to infuse. After that, the infusion is taken three times a day.
  • Motherwort- a tablespoon of motherwort must be poured with 500 ml of boiling water, and then left for 6-8 hours. The ready-made infusion is taken ½ cup three times a day.

Does the penis not rise without stimulation? To normalize erectile function, it is necessary to give up bad habits - first of all, we are talking about smoking and frequent consumption of alcoholic beverages. The maximum allowable dosage is a few glasses of good red wine or beer throughout the week. Such a dose will not harm the reproductive health of a man and will not in any way affect potency.

Synthetic erection stimulants for men

Synthetic stimulants of male potency are pharmacological drugs, the action of which is aimed at restoring erectile function. The main action is aimed at ensuring an abundant flow of blood into the cavernous and cavernous bodies of the penis. Due to this, the penis becomes hard, and sexual intercourse becomes possible.

Male potency stimulants - which ones are better? This question is of interest to every man who is faced with such a problem as deterioration of erection.
To date, the most popular and effective drugs for increasing potency are drugs such as Viagra, Cialis, Levitra, Sildenafil, Tadalafil, Vardenafil. Male potency stimulants, the list of which is presented above, effectively affect potency, normalizing the functioning of the reproductive system.

Which potency stimulant is better? This question cannot be answered unequivocally, since factors such as the age of the man, the severity of erectile dysfunction and the state of health are taken into account when choosing a specific drug. Potency stimulants for men after 60 years of age may differ significantly from those drugs that are used to improve erection in younger men.

Male potency stimulants are used in various ways and have different duration of action:

  • Viagra- male stimulant, the duration of action of the medication is at least 5-6 hours. The drug should be taken immediately one hour before the planned sexual contact, approximately 45–55 minutes after taking the pharmacological drug begins to work. Taking the medication does not depend on food intake and is not addictive.
  • Cialis- stimulant pills for erection. It is recommended to take the medicine about 30-40 minutes before sex. The duration of the action of the drug is at least 24-36 hours, after which it is completely eliminated from the male body in a natural way.
  • Levitra- an effective stimulant of the proportion of male potency, which is not addictive and has a long-lasting effect. The medication should be taken half an hour before the planned intimate contact, its effect will last for 10-12 hours. It is allowed to combine the intake of Levitra with the use of alcoholic beverages - but, of course, within reasonable limits.
  • Tadalafil- the best potency stimulant, according to many representatives of the strong half of humanity. The drug is taken 15–20 minutes before the expected sexual intercourse, while the effect of the drug lasts up to 30–36 hours. This means that during the above period of time, the pathogen for men will provide the required level of erection.

It is important to remember that any stimulants of male potency of synthetic origin are strictly forbidden to use on their own, without first consulting a doctor. Stimulation of erectile function is a serious medical procedure that should be prescribed only after a preliminary examination and all tests. Stimulant drugs are prescribed by the doctor after studying the clinical picture of erectile dysfunction.

Be sure to carefully study the instructions for use. For example, it is extremely important that any synthetic stimulant for men should be taken no more than 2-3 times a week - only in this case, you can count on a lasting positive effect from taking a medication.

Male potency stimulants act on the body according to a single principle - such drugs improve and activate blood circulation in the pelvic organs, due to which the penis becomes hard and it becomes possible to conduct a normal sexual intercourse.

Erectile dysfunction is not a sentence, but a rather serious medical problem, from which you can get rid of with the help of special medications or traditional medicine. It is imperative to correct the usual diet, get rid of bad habits and be patient - and the restoration of male health will not take long.

A large group of drugs used for narcotic purposes include stimulants of the central nervous system, psychostimulants, amphetamines, aphrodisiac drugs, psychotonic drugs, and doping. The most commonly used of them are phenamine (amphetamine), nervitin, peridrol, centhedrine, meredil, ephedrine, theofedrine. the form of thick jelly) and chifir (concentrated tea infusion - 50 g of chifir contains approximately 0.35 g of caffeine), which is obtained by prolonged boiling of tea in a small amount of water. Caffeine is also used in the form of a medication (tablets, injections).

The main pharmacological action of chifir is determined mainly by the content in it of a large amount of caffeine and its alkaloids. This drug enhances and regulates the processes of excitation in the cerebral cortex. However, the effect of chifir is not completely analogous to that of caffeine. This, apparently, is explained by the presence in chifir, in addition to caffeine, numerous substances, essential oils, etc. The same can be said about coffee, where caffeine is contained not in pure form, but in a certain ratio with a large group of other organic substances. Therefore, the body's reaction to coffee and chifir is somewhat different than when taking pure caffeine in the form of a medicine.

In the 70s of the XX century, a drug related to amphetamines appeared - phenmetrazine (preludes), a slang name for wat. At first, it was believed that it was less dangerous than other amphetamines, but these hopes did not materialize. Methylphenidate (Ritalin) was also similar to it.

It is necessary to isolate methyl amphetamines, which are similar in some properties to hallucinogens. One of them is the well-known drug MDMA. For advertising purposes, he was given the enticing name "ecstasy" (in slang - "XTS", "Adam"). It is the prototype "designer" drug and has both hallucinogenic and amphetamine-like properties. The drug is quite toxic. Doses exceeding 100 mg cause toxic effects (perverse perception, visual impairment, hypersensitivity, etc.). This drug is often taken by young people at discos, dance parties. Its easy spread is facilitated by its ease of use - inside in tablets, which come in different colors, sometimes with patterns on the surface. Although taking it seems harmless, it can be fatal as a result of excessive physical exertion and fever caused by the toxic effects of the drug.

A similar drug, similar to the previous one and approximately equal to it in terms of its effect on the body, but less commonly used - dimethoxymethylamphetamine - DOM (in slang - "STP"). It is chemically similar to mescaline and produces similar hallucinatory-visual effects. Also used are methylenedioxyamphetamine - DMA (in slang - "drug of love", "soft"), MDE (in slang - "Eve"), DET and others.

The narcotic effect of stimulants on the human body

Stimulants excite the central nervous system, improve well-being and mood, promote a surge of energy, induce vivacity, a subjective feeling of a surge of strength, relieve fatigue, increase physical and mental performance, general activity and sthenism, and activate mental activity. These drugs also stimulate intellectual activity, speeding up the flow of ideas and associations. At the same time, speech is accelerated, the ease of finding words, switching is felt. There is a general mobilization of efforts and an increase in mental tone, a kind of readiness for action, greater self-confidence, perseverance, determination. Some drugs cause a feeling of power, superiority over others. This can sometimes lead to aggressive tendencies. Many drugs increase blood pressure, heart rate, and breathing.

In medicine, stimulants are used in neurological and psychiatric practice for various depression and other diseases accompanied by drowsiness, lethargy, and are also prescribed during childbirth. In the past, stimulants were used more widely. For example, amphetamines in the 1920s. used to treat obesity, colds, narcolepsy - a disease in which a person sleeps uncontrollably, and, strangely enough, were used in the treatment of hyperactive children and many other diseases. Amphetamines are now rarely used in medical practice, mainly because they are very easy to abuse.

The action of stimulants of the central nervous system is largely related to their effect on the energy processes of the body. However, the mechanism of this action is somewhat different for different agents. For example, phenamine, pervitin increase the resynthesis of ATP in the brain - a substance necessary for normal metabolic processes in the heart muscle and brain cells. Stimulation by caffeine and some other means occurs by increasing the use of energy reserves. Although they increase physical and mental performance, in fact they only mobilize the body's reserve, "spur" it on, acting as if in the role of a whip. The feeling of cheerfulness, clarity of thinking, increased mood, activity does not last long - several hours, giving way to a feeling of fatigue, general weakness, weakness, depression, absent-mindedness, drowsiness, which are the more pronounced and prolonged, the larger the dose of the stimulating substance was taken.

Stimulants gradually impair your ability to remember. These drugs eliminate the physiological need for natural rest and normal recuperation, which ultimately, with prolonged use, can lead to depletion of nerve cells. For narcotic purposes, stimulants are used in high doses, more often inside, less often intravenously. Some of them chew, for example cat. Other ways of using them are also known.

Due to the difficulty in acquiring drugs, drugs made in a homemade way have recently appeared. One of them in the slang of drug addicts is called "shirka" - it is a homemade drug, which is a derivative of pervitin. A rather dangerous drug is ephedrone - a product of artisanal processing of medicines containing ephedrine (ointments and drops from the common cold, some anti-asthma drugs, such as solutan, etc.). In the jargon of drug addicts, ephedrone is called "martsefal", "jeff cocktail", "mulka", "murtsovka", etc. Considering the great danger, ephedrone is included in the number of drugs. Pervitin and ephedrone are phenylalkelamines with amphetamine-like effects. They are administered almost exclusively intravenously, although most amphetamines are taken by mouth.

Stimulants as doping for athletes

Here one cannot fail to mention doping, which, unfortunately, is still widely used by athletes, of course, under conditions of the strictest secrecy. These are, as a rule, substances that stimulate the offensive impulse and vital activity of the body, its stamina and endurance, which contributes to the achievement of higher results that are inaccessible to an athlete under normal conditions. We can say that doping is a whip that artificially and violently spurs the athlete's body, often forcing him to overstep the boundaries of his own capabilities.

Additional articles on this topic:

However, amphetamines have limited medical use in Western countries.)

Drugs from other pharmacological groups, for example, some antidepressants, nootropics, adaptogens (for example, ginseng, pantocrine, eleutherococcus), etc., can also have a psychostimulating effect.

Mechanism of action[ | ]

Psychostimulants release catecholamines from nerve endings and block their reuptake by inhibiting monoamine oxidase. The mechanism of action is associated with the indirect adrenomimetic action of psychostimulants, due to which the excitatory processes in the brain are enhanced.

Drugs [ | ]

5 mg deoxin tablets

Methylphenidate is available in immediate release form and contains a racemic mixture of D, L-methylphenidate; duration of action - 3-4 hours. D-methylphenidate (trade name - "focalin") is 2 times more potent than racemic Ritalin. Ritalin SR is a sustained release L-methylphenidate. In July 2000, a long-acting form of methylphenidate - "concert" was released, which lasts 12 hours: 383. Ritalin LA (long action - long-acting) differs in that the first half of the dose is released quickly, and the second - slowly. Another long acting form, Metadate CD from Celltech Pharmaceuticals, lasts 8 hours.

Psychostimulants used in medicine (mainly in psychiatric practice):

International name Trade name Forms of release and dosage
Methamphetamine Deoxin Tablets: 5 mg
Dexamphetamine Dexedrine Tablets: 5; 10 mg
Dexedrine Spansula Spansulas: 5; ten; 15 mg
Levamphetamine + Dexamphetamine Adderall Tablets: 5; 7.5; ten; 12.5; 15; twenty; 30 mg
Adderall XR Capsules: 5; ten; 15; twenty; 25; 30 mg
Lizdexamphetamine Vivanse
Wenwanse Capsules: 30; 50; 70 mg
Elvanse Capsules: 20; thirty; 40; 50; 60; 70 mg
Tivense Capsules: 30; 50; 70 mg
Methylphenidate Ritalin Tablets: 5; ten; 20 mg
Ritalin SR Tablets: 20 mg
Ritalin LA Capsules: 10; twenty; thirty; 40 mg
Quillivant XR Oral suspension 25 mg / 5 ml
Methylin Chewable tablets: 2.5 5; 10 mg
Oral solution: 5 mg / 5 ml, 10 mg / 5 ml
ER metadat Tablets: 10; 20 mg
CD Metadat Capsules: 10; twenty; 30 mg
Concert Tablets: 18 27; 36; 54 mg
Deutran Transdermal patch: 10; 15; twenty; 30 mg
Dexmethylphenidate Focalin Tablets: 2.5 5; 10 mg
Focalin XR Capsules: 5; ten; 20 mg
Modafinil Provigil Tablets: 100 200 mg
Mesocarb Sydnocarb
(formerly in RF)
Tablets: 5; 10 mg
Feprozidnine Sydnofen
(formerly in RF)
Tablets: 5 mg
Pemoline Betanamine
(Japan)
Tablets: 10; 25; 50 mg
Zielert
(Israel)
Tablets: 18.75; 37.5; 75 mg
Ceractive
(Chile)
Tablets: 37.5 mg

Indications for use[ | ]

In psychiatry, psychostimulants are most often used to treat attention deficit hyperactivity disorder. In addition, they are effective for amotivating conditions and narcolepsy. For adynamic depression, most commonly seen in schizophrenia, psychostimulants can be combined with antidepressants. Also indications for use are apato-abulic, stuporous and substuporous states; neurotic disorders with lethargy; asthenic conditions, accompanied by lethargy, apathy, drowsiness.

Indications for the use of psychostimulants are also a decrease in the ability to concentrate, increased mental fatigue, a decrease in physical performance and rapid intellectual exhaustion with neuroinfections, intoxication, craniocerebral trauma, cerebrovascular accidents, and previous somatic diseases. Also psychostimulants are effective in astheno-hypochondriac and astheno-depressive syndromes and alcohol withdrawal syndrome after alcohol withdrawal.

They can be used to improve mood and interest in life in severely somatic patients with apathy and social isolation.

Psychostimulants can also be used to reduce the need for narcotic analgesics in terminal cancer patients. They also counteract the over-sedating effects of analgesics.

Caffeine is used to eliminate drowsiness, increase mental and physical performance, as well as in case of poisoning with drugs that depress the central nervous system and hypotension.

ADHD [ | ]

The sustained release forms of methamphetamine, methylphenidate and dextroamphetamine have not been fully proven to be effective: 494.

Narcolepsy [ | ]

Psychostimulants are used to relieve daytime sleepiness and sleep episodes in narcolepsy. They are not effective against catalepsy.

Depression [ | ]

Sometimes psychostimulants are used off-label for the treatment of clinical depression and bipolar disorder, in particular for the treatment of atypical depression and resistant depression.

Schizophrenic spectrum disorders[ | ]

In patients with schizophrenia in remission, psychostimulants have a mild stimulating effect: 396.

Low-dose psychostimulants have also been used to relieve weakness and sedation in schizophrenia caused by typical antipsychotics and clozapine, with no exacerbation of psychosis: 215.

Acquired immune deficiency syndrome[ | ]

Obesity [ | ]

Complications [ | ]

Psychostimulants can cause mental dependence, insomnia, anorexia, irritability, sometimes tachycardia, and high blood pressure. With chronic abuse, stimulatory psychosis is possible. In mentally ill psychostimulants can provoke an exacerbation of psychotic symptoms. In particular, amphetamine can exacerbate positive symptoms in people with schizophrenia. Also, psychostimulants tend to worsen the course of Tourette's syndrome.

List of psychostimulants[ | ]

Some stimulant substances
  • Phenylethylamines, in particular
  • Oxazolines

Notes (edit) [ | ]

  1. Belova E. I. Psychostimulants// Fundamentals of neuropharmacology: Textbook. manual for university students. - M.: Aspect Press, 2006 .-- P. 120 .-- 176 p. - ISBN 5-7567-0403-5.
  2. O. Syropyatov, N. Dzeruzhinskaya, E. Aladysheva. Psychostimulants// Fundamentals of psychopharmacotherapy: a guide for doctors. - Liters, 2015 .-- S. 153 .-- 2825 p.
  3. A. Lukovkina. Psychostimulants// Pharmacology. Lecture notes for universities. - Liters, 2015 .-- S. 129 .-- ISBN 978-5-45-775271-9.
  4. Pharmacology / under. ed. YF Krylov and VM Bobyrev. - M., 1999.
  5. Alan F. Schatzberg, Jonathan O. Cole, Charles DeBattista. Manual of Clinical Psychopharmacology = Manual of Clinical Psychopharmacology. - M.: MEDpress-inform, 2014 .-- 608 p. - ISBN 978-5-00030-101-2.
  6. Adderall XR Prescribing Information (unspecified) . Food and Drug Administration... Retrieved February 24, 2017.(English)
  7. Desoxyn Prescribing Information (unspecified) . Food and Drug Administration... Retrieved February 24, 2017.(English)
  8. Conners C. K., Taylor E. (1980). “Pemoline, methylphenidate, and placebo in children with minimal brain dysfunction”. Arch gen psychiatry. 37 (8): 922-30. PMID.
  9. Vyvanse Prescribing Information (unspecified) . Food and Drug Administration(2015). Retrieved February 28, 2017.
  10. Stimulants Used to Treat Attention Deficit Hyperactivity Disorder (ADHD) (unspecified) . Food and Drug Administration... Retrieved March 11, 2017. Archived March 12, 2017.(English)
  11. V. N. Stock Pharmacotherapy in Neurology: A Practical Guide. - 3rd ed., Erased. - M.: LLC "Medical Information Agency", 2003. - S. 61-62. - 301 p. - ISBN 5-89481-123-6.
  12. Arana J., Rosenbaum J. Handbook of Psychiatric Drug Therapy. - M.: Publishing house BINOM, 2004 .-- 416 p. - ISBN 5-9518-0098-6.
  13. Dulcan MK. Using psychostimulants to treat behavioral disorders of children and adolescents. J Child Adolesc Psychopharmacol 1990; 1: 7-20
  14. Klein RG, Wender P. The role of methylphenidate in psychiatry. Arch Gen Psychiatry 1995; 52: 429-433.
  15. Swanson J. M., McBurnett K., Christian D. L., Wigal T. (1995). Stimulant medication and the treatment of children with ADHD. In TH Ollendick & RJ Prinz (Eds.), Advances in Clinical Chil Psychology, 17, 265-322. New York: Plenum Press
  16. Stotz, Gabriele; Woggon, Brigitte; Angst, Jules (1999-12-01). “Psychostimulants in the therapy of treatment-resistant depression Review of the literature and findings from a retrospective study in 65 depressed patients”. Dialogues in Clinical Neuroscience. 1 (3): 165-174.

Stimulants are conventionally divided into 4 large groups:

1. PSYCHOSTIMULANTS

a) psychomotor:

Phenamine;

Sydnocarb.

b) psychometabolic (nootropics):

Nootropil (piracetam);

Cerebrolysin;

Gamalon and others.

2. ANALEPTICS

a) direct action:

Bemegrid;

Etimizole et al.

b) reflex action:

Tsititon and others.

c) mixed action:

Cordiamin, etc.

3. SPINAL CORD STIMULANTS

Strychnine;

Sekurenin and others.

4. SESETONIZING AGENTS (ADAPTOGENS)

a) of plant origin:

Ginseng preparations, Eleutherococcus

ka, aralia, golden root, ma

raliego root, Bittner's balm and

b) animal origin:

Pantokrin and others.

PSYCHOSTIMULATORS and NOTROPES

PSYCHOSTIMULATORS

Psychostimulants (or psychotonics, psychoanaleptics, psychomotor stimulants) increase mood, the ability to perceive external stimuli, psychomotor activity. They reduce the feeling of fatigue, increase physical and mental performance (especially when tired), temporarily reduce the need for sleep (drugs that invigorate the tired body are called "doping" - from English to dope - to give drugs).

Unlike drugs that depress the central nervous system, stimulants are less important, since they are devoid of selectivity of action. In addition, stimulation of the central nervous system is accompanied by its subsequent depression.

Classification of psychostimulants

1) Funds acting directly on the central nervous system:

a) stimulating mainly the cerebral cortex (xanthine alkaloids, phenamine, sydnocarb, methylphenamine, meridol, etc.);

b) stimulating mainly the medulla oblongata (cortex

ash, cordiamine, bemegrid, camphor, carbon dioxide);

c) stimulating mainly the spinal cord (strychnine).

2) Means acting on the central nervous system reflexively(lobelin, verat

room, nicotine).

It should be remembered that such a division is conditional and, when used in large doses, they can stimulate the central nervous system as a whole.

A typical representative of psychostimulants is FENAMIN(amphetamine sulfate; tab. at 0, 005; drops in the nose, in the eye 1% solution). Chemically it is phenylalkylamine, that is, it is similar in structure to adrenaline and norepinephrine.

MECHANISM OF ACTION associated with the ability to release from presynaptic endings NORADRENALINE and DOPAMINE. In addition, phenamine reduces the reuptake of norepinephrine and dopamine.

Phenamine stimulates the ascending activating reticular formation of the brainstem.

PHARMACOLOGICAL EFFECTS

EFFECTS ON THE CNS

A powerful stimulant of the central nervous system. It increases mental and physical performance, improves mood, causes euphoria, insomnia, tremors, anxiety. In therapeutic doses, it has an awakening effect, eliminates fatigue, and increases physical capabilities. Stimulates the respiratory center and in this regard acts as an analeptic.

EFFECTS ON THE CARDIOVASCULAR SYSTEM

Increases both systolic and diastolic blood pressure. In relation to the hypertensive effect of phenamine, tachyphylaxis is known.

SMOOTH MUSCULATION

Phenamine increases the tone of the bladder sphincter and relaxes the muscles of the bronchi, but only at high doses. Phenamine reduces appetite (for the hypothalamus), has some anticonvulsant effect (with Petit mal).

Stimulants that affect the central nervous system include substances that cause a feeling of vigor and have a tonic effect on the body. Narcotic stimulants accelerate the processes occurring in human systems and organs. The result of the action is the elimination of fatigue, drowsiness, activation of memory, brain activity and physical activity.

Their beneficial properties can support a person in difficult times, but their abuse leads to dependence and deterioration of health over time. The purpose of these drugs is to treat patients with mental disorders, but they are not always used for this purpose. Sometimes they are taken to overcome fear, insecurity, replenish strength after physical exertion. That is to give an impetus to increase the endurance threshold and for a good mood.

Common psychostimulants include legal light drugs and illegal heavy drugs. The former include caffeine and nicotine, adaptogens and analeptics, the latter - methamphetamines, amphetamines, ecstasy, the sale of which is a criminal offense. Legal stimulants are used by most people, as they are found in tea, coffee and other products that are on our table every day. In order to increase concentration and get the desired stimulation of activity, many brew strong coffee or make chifir. Smokers get their share of the pleasure of tobacco, those who can buy ephedrine at the pharmacy take it to feel a boost in strength and mood.

These are all light allowed stimulants that everyone can take in different life situations.

Heavy stimulants have a stronger effect, they are called narcotic, since psychological dependence develops for them, which requires treatment in a specialized clinic. Long-term use of such substances leads to pathological disorders in systems and organs, changes the human psyche, and leads to personality degradation.

The group of hard narcotic stimulants includes:

  • amphetamines under the slang name of speed,
  • methamphetamines, called mevitin or vint by addicts,
  • cocaine,
  • dexamphetamine,
  • crack.

The mechanism of action of these drugs is a deep effect on the central nervous system, brain receptors and changes in reactions. Regular use of them causes intoxication, with the cancellation of the reception, psychosis occurs.


The emergence of stimulants and their distribution

In folk medicine, plant adaptogens have been used since ancient times, for example, ginseng root, echinacea, radiola rosea, eleutherococcus, zamanihi, lemongrass, aralia. Active use is typical for organic matter obtained from the horns of the maral. Popular among the population are dietary supplements related to actoprotectors and increasing efficiency.

There is nothing wrong with increasing endurance and giving the body an additional stimulus. Stimulants are often used by athletes, people striving to achieve a lot in life, students during a session. Doctors also recommend using natural bioactive substances, for example, to restore potency, get rid of chronic fatigue, and raise vitality.

In addition to positive examples of the use of psychoactive components of plant origin, there are negative factors in the use of stimulants. It is known that with their help the Japanese kamikaze went to their death. The feeling of fear was dulled by psychotropics in German soldiers during the war. But the first cases of the use of stimulants of the central nervous system were noted already in antiquity. The Indians drank drinks from coca leaves and chewed them in order to "rejuvenate the body", in Europe they met coca after the Spaniards brought it from the Andes.

The first attempts to artificially produce psychostimulants include the synthesis of methamphetamine in Germany. This happened in 1887, and then Japan took over and a stronger form of plant-based stimulant emerged. Methamphetamine became widespread during the First World War. Then this psychoactive substance began to be used in the United States and other countries, as a medicine against obesity and depression. Its free sale led to the emergence of a large number of people dependent on it, and it was banned. After that, clandestine laboratories for the production of synthetic stimulants were organized in different countries, which operate to this day.

Light stimulants

Caffeine and nicotine are legal stimulants used by millions of people. Caffeine is found in coffee beans, cola nuts. There are forms of matter synthesized artificially. In moderate doses, caffeine is beneficial because it relieves drowsiness, fatigue, and revitalizes the brain.

The principle of influence on the central nervous system consists in the following effects:

  • stimulating effect on the cerebral cortex;
  • activating effect on metabolic processes;
  • stimulation of mental activity;
  • increased efficiency.

But the benefits of caffeine are only found in people with strong nervous systems. For those with weakened nerves, caffeine is not recommended. Since its presence in the body causes additional irritation, which gradually depletes the nervous system.

Hypertensive patients should also give up caffeine. It has the ability to increase blood pressure, but for migraine sufferers, it is useful for relieving pain and spasms in combination with analgesics.

Nicotine ranks second in popularity. The substance is an alkaloid and is found in the leaves of tobacco, it differs in that it causes a quick and persistent addiction. In this case, it does not matter in what form the alkaloid is introduced into the body when smoking, chewing, sniffing tobacco or nasvay, addiction develops from all forms.

The first dose of nicotine causes a relaxing effect, unpleasant dizziness and tremors of the limbs. Subsequent doses are easier to tolerate, and when addicted, addicts note positive aspects of the smoked cigarette:

  • short-term memory is stimulated;
  • composure appears;
  • attention is activated;
  • increased tone is observed in addicts for half an hour, then the addict needs a new dose.

Regular smoking is already an addiction, it needs to be treated, as the consequences are sad. The nervous, cardiovascular, respiratory systems suffer, the skin color deteriorates, memory and intellectual abilities decrease. It is difficult to fight nicotine addiction, so it is better to go to a drug treatment clinic, where they know how to heal from tobacco addiction.

Ephedrine is popular among athletes and those who are losing weight. It is a stimulant derived from the leaves of evergreen ephedra. This alkaloid is used in medicine to treat asthma, drug intoxication, allergies. You can buy the drug only with a prescription, since it is considered a potent stimulant of the nervous system and causes undesirable phenomena:

  • significantly reduces the pain threshold, which can be dangerous under certain circumstances;
  • encourages physical activity, the person does not understand in time that critical fatigue has come;
  • the number of heartbeats is growing;
  • pressure rises.

A strong tonic effect is not without consequences, the nervous system is depleted, and dependence on the drug develops. Cancellation of ephedrine is fraught with a breakdown and severe depression.

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Heavy stimulants

Cocaine, amphetamines and methamphetamines are considered strong narcotic stimulants. They are classified as severe and bring more significant negative consequences for the body and psyche than light ones.

Cocaine

Cocaine is obtained from the leaves of the coca bush, it is a herbal psychostimulant and was used by the tribes of the ancient Indians to increase tone and vitality. But it was natural when the leaves were simply chewed, and now it is a concentrated powder for inhalation, which causes the following effects:

Cocaine addicts gradually become, in order to achieve the desired pleasure, the dose has to be increased. As a result, after frequent overexcitation and euphoric states, sleep loss occurs, blood pressure rises, and heart rhythm is disturbed.

Crack

Not every addict can buy cocaine regularly because it is expensive. For drug addicts with limited resources, drug dealers offer a variety of cocaine, crack. Smoking this drug means getting addicted faster and experiencing stronger feelings than when using cocaine:

  • euphoria is more prolonged;
  • a person feels a great surge of physical strength and mental capabilities;
  • the sensitivity increases significantly.

Such a powerful stimulation of the central nervous system ends with its exhaustion, hallucinations and imbalance of the whole organism. During the withdrawal period, depressive states and psychosis occur.

Amphetamines

These are common synthetic stimulants. Their consumers are young people, in particular students. Under the influence of amphetamine, they can successfully pass exams, study at night, earn extra money after lectures without feeling tired at all. Raising your endurance threshold is what attracts and makes you addicted to a stimulant.

The principle of the substance's action is the production of the stress hormone - adrenaline. The adrenaline rush makes a person as active as possible in all areas:

  • he is able to solve mental problems;
  • perform increased physical activity,
  • not paying attention to pain;
  • do not sleep for a long time;
  • go without food.

Decreased appetite from amphetamine has made this narcotic stimulant popular among those looking to gain a slender figure. Fat burning also goes through increased physical activity. The activation of internal reserves ends with their excessive expenditure and loss of health. And the feeling of high you get when taking a psychostimulant causes dependence on it.

Methamphetamine

This substance is similar in action to amphetamine. The principles of influence on the body are the same, but the effect is stronger. It causes a powerful mobilization of internal reserves, a person can go without sleep for several days, while his physical strength does not decrease, he does not feel tired.

The difference between this psychostimulant is instant addiction, dependence develops from the first dose. This makes meth more dangerous than amphetamine.

Effects on the body

After the first techniques, psychostimulants cause an increase in physical and mental potential, mobilize a person to perform difficult tasks, make him hardy and energetic. But excessive exertion leaves a negative mark and leads to loss of health.

Such pathological prospects after regular use of psychostimulant substances include the occurrence of various dysfunctions:

  • dizziness;
  • nausea;
  • loss of appetite and, as a result, rapid weight loss;
  • heart rhythm disturbances;
  • emotional instability.

At the same time, the harm from narcotic stimulants is much greater than the benefits.

How does addiction come about?

Addiction arises to any stimulants, including light and heavy ones. A prime example is the inability to go without coffee or the habit of smoking. Psychological dependence is formed to strong stimulants. Cancellation of them leads to nervous breakdowns and depression. It is necessary to remove addicts from this state with the help of professionals; the treatment is carried out comprehensively with a medication course and rehabilitation. The healing process can take months.

Why are narcotic stimulants dangerous?

Those who believe that a single use of a stimulant will not lead to negative consequences will have to be disappointed. Even a single dose will affect the psyche. A person will want to repeat the effect of pleasure, excitement and euphoria. That is, the first high is a step towards addiction.

The next steps are the road to destruction of health and psyche. Long-term use ends with depression, fears and suicidal tendencies. Insomnia and overexcitement drain the nervous system, and loss of appetite leads to poor health. Addiction to psychostimulants ends with psychosis and premature aging of the whole organism, sometimes death from excessive stress on systems and organs.

Brain and psychostimulants

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